The Genomic study of Chronic Lymphocytic Leukaemia
The International Cancer Genome Consortium is an international effort to establish a comprehensive descriptionof genomic, transcriptomic and epigenomic changes in50 different tumor types and/or subtypes which are of clinical and societal importance across the globe. Spain’scontribution to the ICGC...
Coordinator: Elias Campo & Carlos López-Otín
Elucidating structural variation in primate genomes
The PRIMATE project aims to discover the extent of genome structural polymorphism within the great ape species by generating next-generation sequencing datasets at high coverage from multiple individuals of diverse species and subspecies, characterizing structural variants and validating them...
Coordinator: Tomàs Marquès-Bonet
Development of new statistical tools for improving the detection of population substructure at individual level with applications in humans
Detecting population substructure in Homo sapiens from the genetic diversity of the species is cumbersome given its evolutionary history and recent origin. Nevertheless, population substructure represents a serious threat when conducting GWAS and properly identifying its signature is essential for...
Coordinator: Oscar Lao