Promoting SINgle cell GEnomics to explore the ecology and evolution of hidden microeuKaryotes
Microbial eukariotes cover the widest phylogenetic diversity in the eukaryotic tree of life and are essential components of all Earth’s ecosystems. Paradoxically, they remain large unknown, hiding a wealth of genes and genomes that are key to understand the ecology and evolution of microbial...
Coordinator: Ramon Massana (ICM-CSIC, Spain)
Breast CAncer STratification - Understanding the determinants of risk and prognosis of molecular breast cancer subtypes. The aim of B-CAST is to identify women at moderate to high risk of breast cancer, the subtype of cancer that is most likely to develo
The B-CAST project (Breast CAncer STratification) is coordinated by the Netherlands Cancer Institute Antoni Van Leeuwenhoek and it will be conducted over five years (until September 2020). Breast tumours are heterogeneous, and result from the complex interplay of multiple lifestyle/environmental...
Coordinator: Marjanka Schmidt
A distributed infrastructure for life-science information - Building a sustainable European infrastructure for biological information, supporting life science research and its translation to medicine, agriculture, bioindustries and society
From September 2015, ‘ELIXIR-EXCELERATE’ is facilitating the integration of Europe’s bioinformatics resources, supporting all sectors of life-science R&D. It will deliver excellence to ELIXIR’s users by fast-tracking the development and deployment of essential data services. EXCELERATE funding...
Coordinator: Niklas Bloomberg
Dynamics of human genome architecture in stable and transient gene expression changes
The classical view of genomes as linear sequences has been replaced by a vision of nuclear organization that is both dynamic and complex, with chromosomes and genes non-randomly positioned in the nucleus. Process compartmentalization and spatial location of genes modulate the transcriptional output...
Coordinator: Miguel Beato
The Genomic study of Chronic Lymphocytic Leukaemia
The International Cancer Genome Consortium is an international effort to establish a comprehensive descriptionof genomic, transcriptomic and epigenomic changes in50 different tumor types and/or subtypes which are of clinical and societal importance across the globe. Spain’scontribution to the ICGC...
Coordinator: Elias Campo & Carlos López-Otín
Elucidating structural variation in primate genomes
The PRIMATE project aims to discover the extent of genome structural polymorphism within the great ape species by generating next-generation sequencing datasets at high coverage from multiple individuals of diverse species and subspecies, characterizing structural variants and validating them...
Coordinator: Tomàs Marquès-Bonet

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